Sugammadex Development and Use in Clinical Practice
نویسندگان
چکیده
منابع مشابه
Use of sugammadex in clinical practice
neostigmine), reverses neuromuscular blockade rapidly and effectively by encapsulating free circulating steroidal neuromuscular blocking agents (e.g., rocuronium) directly [1]. Moreover, sugammadex does not have muscarinic properties, whereas neostigmine has significant adverse muscarinic effects. Therefore, sugammadex is used in many countries as a new neuromuscular reversal agent to antagoniz...
متن کاملSugammadex: clinical development and practical use
SUGAMMADEX IS BELONGING TO A NEW CLASS OF DRUGS the selective relaxant binding agents. Sugammadex can reverse residual paralysis by encapsulating free circulating non depolarizing muscle relaxants. The mains advantages of sugammadex when compared with conventional anticholinesterase agents are a much faster recovery time and the unique ability, for the first time, to reverse rapidly and efficie...
متن کاملSugammadex in clinical practice.
The availability of sugammadex allows greater flexibility in the use of rocuronium and vecuronium during anaesthesia and surgery. The neuromuscular block induced by both drugs can be reversed from both superficial and deep levels of block by adjusting the dose of sugammadex. The dose of sugammadex for reversal of shallow block produced by these neuromuscular blocking drugs is approximately 2 mg...
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provided the original work is properly cited. CC Curare, which is the source of modern muscle relaxants, was used for centuries by South American Indians for hunting. On January 23, 1942, Harold R. Griffith and a resident Enid Johnson administered curare (intocostrin) to a patient undergoing an appendectomy, and this was the first clinical use of curare [1]. After World War II, Dr. Cecil Gray a...
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Many anti-diabetic drugs with different mechanisms of action are now available for treatment of type 2 diabetes mellitus. Sulfonylureas have been extensively used for treatment of type 2 diabetes for nearly 50 years and, even in our times, are widely used for treatment of this devastating chronic illness. Here, we review some of the available data on sulfonylureas, evaluating their mechanism of...
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ژورنال
عنوان ژورنال: Current Anesthesiology Reports
سال: 2013
ISSN: 2167-6275
DOI: 10.1007/s40140-013-0015-8